不过，传统冷冻电镜本质上仍是“静态摄影”，它捕捉的是分子在某一瞬间的构象。要真正理解生命，不仅要知道“它长什么样”，更要明白“它是怎么动的”。近年来，科学家又开发出时间分辨冷冻电镜，在生物反应启动后的特定时间点快速冷冻样本，再通过一系列“时间切片”，复现分子变化的全过程。
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