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细胞实验显示这两种CAR都能提高星形胶质细胞摄取Aβ的能力,Cre-Megf10更突出,Adu-Dectin1还能促进小胶质细胞吞噬;小鼠体内实验表明Adu-Dectin1可明显提升脑内星形胶质细胞对Aβ的摄取,两种CAR在AD模型小鼠脑中能稳定表达较长时间,阳性细胞会聚集在淀粉样斑块周围,这些结果说明Cre-Megf10和Adu-Dectin1这两种CAR疗法值得进一步开展更大规模的体内研究。,这一点在PDF资料中也有详细论述
。新收录的资料是该领域的重要参考
When you have an optional and want a fallback:,推荐阅读新收录的资料获取更多信息
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And, what will happen to some of our most revered and beloved landscapes like the Lake District, Yorkshire Dales, Scottish Highlands and Welsh mountains, and the people who live and work there?