Nyren’s sequencing method earned the name “pyrosequencing” since it revolved around the production of pyrophosphate. At first, pyrosequencing could sequence only short DNA snippets, with a few nucleotides. In 1996, however, Nyren’s lab demonstrated sequencing of up to 15 bases by using a modified “A” nucleotide to reduce their signal-to-noise ratio.7 In 1998, they increased this to 34 bases by adding another enzyme, called apyrase, to the mix; apyrase degraded unincorporated nucleotides, removing the need for constant wash steps.
even a useful prototype. (If you’d like a more nuanced take, Chris’s
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此外，在上述时间段内，德硕科技的资产负债率分别为67.34%、65.28%、66.66%、65.88%，同行可比公司平均值公司平均值分别为37.03%、36.84%、37.81%、37.63%，资产负债率始终高于同行均值28个百分点以上，债务压力显著。。关于这个话题，heLLoword翻译官方下载提供了深入分析